职称：副研究员

学位：博士

电话：13437159527

邮箱：gongyl@mail.hzau.edu.cn

研究方向：1.水产动物氨基酸代谢；2.新型水产饲料蛋白源开发；3.鱼类适应性代谢策略

教育经历

2015.9-2021.01   中国科学院水生生物研究所 水产养殖学 农学博士

2019.10-2020.10  美国范德堡大学  医学院 分子生理学 联合培养

2011.9-2015.6    437ccm·必赢国际  437437必赢国际网址 水族科学与技术 农学学士

工作简历

2023.12-至今  437ccm·必赢国际  437437必赢国际网址  副研究员，硕士生导师

2023.05-2023.11  复旦大学  生物医学研究院 生物学 博士后

2021.02-2023.04  中国科学院水生生物研究所 生物学 博士后

主要奖励情况

国家资助博士后研究人员计划（2023）

上海市“超级博士后”激励计划（2023）

科研项目

1. 国家自然科学基金青年项目（32403039），执行期间：2025.01-2027.12，主持

2. 国家重点研发计划项目“海洋农业与淡水渔业科技创新”（2024YFD2402001）子课题，执行期间：2024.12—2027.11，主持

3. 中央高校基本科研业务费专项基金（510324040），2024.01-2026.12，主持

4. 中国博士后科学基金面上资助（2022M713324），执行期间：2022.06-2024.06，主持

5. 湖北省博士后创新研究岗位，执行期间：2021.09-2023.09，主持

6. 国家特色淡水鱼产业技术体系岗位科学家（CARS-46），执行期间：2021-2025，参与

代表性论文

1. Yulong Gong^#, Bingyuan Yang^#, Dingdong Zhang, Yue Zhang, Zihan Tang, Liu Yang, Katie C Coates, Linlin Yin, Brittney A Covington, Ravi S Patel, Walter A Siv, Katelyn Sellick, Matthew Shou, Wenhan Chang, E Danielle Dean, Alvin C Powers, Wenbiao Chen. Hyperaminoacidemia induces pancreatic α cell proliferation via synergism between mTORC1 and CaSR-Gq signaling pathways. Nature Communications 2023, 14: 235.

2. Yulong Gong, Bingyuan Yang, Wenbiao Chen. Systematic genome editing of the genes spanning an entire chromosome by CRISPR/Cas9 in a vertebrate—zebrafish (Danio rerio). Science China life sciences 2020, s11427-020-1639-4.

3. Yulong Gong^#, Qisheng Lu^#, Longwei Xi, Yulong Liu, Bingyuan Yang, Jingzhi Su, Haokun Liu, Junyan Jin, Zhimin Zhang, Yunxia Yang, Xiaoming Zhu, Shouqi Xie, and Dong Han*. F6P/G6P-mediated ChREBP activation promotes the insulin resistance-driven hepatic lipid deposition in zebrafish. Journal of Nutritional Biochemistry 2023, 122: 109452.

4. Yulong Gong, Weijun Chen, Dong Han*, Xiaoming Zhu, Yunxia Yang, Junyan Jin, Haokun Liu, Shouqi Xie. Effects of food restriction on growth, body composition and gene expression related in regulation of lipid metabolism and food intake in grass carp. Aquaculture 2017, 469: 28-35.

5. Yulong Gong, Longwei Xi, Yulong Liu, Qisheng Lu, Zhimin Zhang, Haokun Liu, Junyan Jin, Yunxia Yang, Xiaoming Zhu, Shouqi Xie*, Dong Han*. Sequential activations of ChREBP and SREBP1 signals regulate the high carbohydrate diet-induced hepatic lipid deposition in gibel carp (Carassius gibelio). Aquaculture Nutrition 2023, 6672985.

6. Bingyuan Yang^#, Gang Zhai^#, Yulong Gong^#, Jingzhi Su, Xuyan Peng, Guohui Shang, Dong Han*, Junyan Jin, Haokun Liu, Zhenyu Du, Zhan Yin, and Shouqi Xie. Different physiological roles of insulin receptors in mediating nutrient metabolism in zebrafish. American Journal of Physiology-Endocrinology and Metabolism 2018, 315: E38-E51.

7. Yulong Gong^#, Gang Zhai^#, Jingzhi Su, Bingyuan Yang, Junyan Jin, Haokun Liu, Zhan Yin*, Shouqi Xie, Dong Han*. Different roles of insulin receptor a and b in maintaining blood glucose homeostasis in zebrafish. General and Comparative Endocrinology 2018, 269:33-45.

8. Yulong Gong, Fan Yang, Junpeng Hu, Cui Liu, Haokun Liu*, Dong Han, Junyan Jin, Yunxia Yang, Xiaoming Zhu, Jianhua Yi, Shouqi Xie. Effects of dietary yeast hydrolysate on the growth, antioxidant response, immune response and disease resistance of largemouth bass (Micropterus salmoides). Fish & Shellfish Immunology 2019, 94:548-557.

9. Yulong Gong, Qisheng Lu, Yulong Liu, Longwei Xi, Zhimin Zhang, Haokun Liu, Junyan Jin, Yunxia Yang, Xiaoming Zhu, Shouqi Xie, Dong Han. Dietary berberine alleviates high carbohydrate diet-induced intestinal damages and improves lipid metabolism in largemouth bass (Micropterus salmoides). Frontiers in Nutrition 2022, 23:1010859.

10. Qisheng Lu^#, Yulong Gong^#, Longwei Xi, Yulong Liu, Wenjie Xu, Haokun Liu, Junyan Jin, Zhimin Zhang, Yunxia Yang, Xiaoming Zhu, Shouqi Xie, Dong Han. Feed restriction alleviates chronic thermal stress-induced liver oxidation and damages via reducing lipid accumulation in channel catfish (Ictalurus punctatus). Antioxidants 2022,11:980.

11. Bingyuan Yang^#, Gang Zhai^#, Yulong Gong, Jingzhi Su, Dong Han*, Zhan Yin, Shouqi Xie. Depletion of insulin receptors leads to β-cell hyperplasia in zebrafish. Science Bulletin 2017, 62: 486-492.

12. Yulong Liu^#, Gang Zhai^#, Jingzhi Su^#, Yulong Gong, Binyuan Yang, Qisheng Lu, Longwei Xi, Yutong Zheng, Jingyue Cao, Haokun Liu, Junyan Jin, Zhimin Zhang, Yunxia Yang, Xiaoming Zhu, Zhongwei Wang, Gaorui Gong, Jie Mei, Zhan Yin, Rodolphe E. Gozlan, Shouqi Xie*, and Dong Han*. The Chinese longsnout catfish genome provides novel insights into the feeding preference and corresponding metabolic strategy of carnivores. Genome Research, 2024, 34:1-16.

13. Bingyuan Yang, Liu Yang, Yueyang Wang, Lisette A. Maddison, Zihan Tang, Sander Haigh, Yulong Gong, Yue Zhang, Brittney A. Covington, Karin J. Bosma, Xin Tong, Patrick Page-McCaw, Maureen Gannon, Qing Deng, Wenbiao Chen. Macrophages and neutrophils are necessary for ER stress-induced β cell loss. Cell Reports 2022, 40, 111255.

14. Katie C. Coate, Chunhua Dai, jay Singh, Jade Stanley, Brittney A. Covington, Amber Bradley, Favour Oladipupo, Yulong Gong, Scott Wisniewski, Katelyn Sellick, Erick Spears, Greg Poffenberger, Anna Marie R. Schornack, Alexandria Bustabad, Tyler Rodgers, Nandita Dey, Leonard D. Shultz, Dale L. Greiner, Hai Yan, Alvin C. Powers*, Wenbiao Chen*, E. Danielle Dean*. Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners. Molecular Metabolism, 2024, 90: 102050.

15. Chunhua Dai^#, Yue Zhang^#, Yulong Gong, Amber Bradley, Zihan Tang, Katelyn Sellick, Shristi Shrestha, Erick Spears, Brittney A. Covington, Jade Stanley, Regina Jenkins, Tiffany M. Richardson, Rebekah A.Brantley, Katie Coate, Diane C. Saunders, Jordan J. Wright, Marcela Brissova, E. Danielle Dean, Alvin C. Powers*, and Wenbiao Chen*. Hyperaminoacidemia from interrupted glucagon signaling increases pancreatic acinar cell proliferation and size via mTORC1 and YAP pathways. iScience, 2024, 27, 111447.

备注

欢迎对水产动物代谢调控、新型饲料原料开发及鱼类适应性代谢策略感兴趣的同学联系报考！